世纪大会堂位于4号楼，可容纳2500人。配有三间贵宾休息室，室内采用红棉花图案装饰，极富岭南特色。配备世界一流的声光系统和国际先进的美国EV音响系统。同时，配备电子表决报到系统、会场监控系统、电子信息屏蔽系统等，能够满足不同规模、类型的接待需要。天鹅湖、巴黎圣母院音乐剧、欧派年会、立白集团年会、UCLG国际友城大会、亚洲能源论坛、省市人大、政协、党代会等国内外会议曾在此举行。
Century Hall is located in Building No.4. It can accommodate 2,500 people and has three VIP lounges. The Hall is decorated with kapok patterns which fully reflects Lingnan features. In addition to the world-class sound and light system as well as the international advanced American EV sound system, it is equipped with other systems including electronic voting reporting system, venue monitoring system and electronic information shielding system.